єχтяαναgαηтєηzумє

Disease usually results from inconclusive negotiations for symbiosis, an overstepping of the line by one side or the other, a biological misinterpretation of the borders.

— Lewis Thomas

  • 45 Posts
  • 41 Comments
Joined 10 months ago
cake
Cake day: May 18th, 2024

help-circle

  • So, the term Fediverse basically refers to the ActivityPub protocol and the associated server software. Technically, it’s not just ActivityPub, but also the AT protocol and nostr. Another layer to the Fediverse, at least in my mind, is having some federation. Meaning Bluesky isn’t apart of the Fediverse, even though it’s built on the AT Protocol, because of it’s isolation. Since there’s no interaction with Lemmy, Mastodon, PixelFed, or other federated social networks, it’s not part of the Fediverse.








  • Well, this was the case maybe 5 years ago, if not 10+ years back. Linux Mint, Ubuntu, PopOS, Fedora, and ElementaryOS can all be run via a GUI. Additionally, you’re comment about programs is baseless. If you switch from Windows to Mac guess what will have to happen, you’ll have to start using similar but not the same programs. However, using a VM or Wine isn’t hard whatsoever thanks to YT walkthroughs. It’s 10 to 20 minutes of guided clicking and then you’re running Windows programs on Linux.

    96% of the top 1,000,000 servers online and 100% of super computers run Linux. But people are creatures of habit and when compounded with a statement like this riddled with half truths, it only makes most folks more hesitant to switch. 4.1% of PCs run a common Linux distro, 1.9% run ChromeOS, and 6.4% run an “unknown” OS, which is widely believed to be Linux as well. So 12.4% of PC’s run some form of Linux and with the SteamOS release around the corner, this will breach 15% for sure. But okay, we’re a bunch of loons who like owning the equipment we bought and enjoy the financial + security + privacy perks of open sourced software. If nothing else, I hope you feel better. Take care!





  • You’re not wrong there, hopefully the pathogen is sequenced soon and researchers start working on an approach to prevent further spread and treat those already infected.

    The fact the numbers are like this in a remote area of Africa demonstrates when it gets to a more dense population, it will only get worse. More viral infections means more mutations. A virus will always mutate, it’s how they survive. These mutations almost always result in a novel version of the virus better adept to spread in the host’s population. There’s also a good portion of these new versions which are no longer infectious as well. It’s basically a numbers game for the virus.

    But Disease X by definition will always start in one specific area, then spread throughout the population.


  • Disease X is actually a concept. In academia, Disease X is covered in infectious disease focused courses, it is a placeholder concept referring to a pandemic pathogen which has not yet been characterized. Its purpose is to encourage proactive thinking and research about pathogens that could cause a pandemic. To see the term thrown around is pretty wild, but hopefully it’s a bit of an overzealous or incorrect use of it. Not even sure if there’s enough data available yet to classify it as Disease X, but it’s Ro value is steadily on the rise, which is always concerning for a novel pathogen.




















  • We’ve known since at least March that about 10 human cases of this new bird flu would allow the virus to mutate and adapt to humans. This is the 14th reported case in the states this year, and the first which could have been transmitted from human to human. We understood what was happening, yet have really done nothing to try to prevent it’s spread.

    The mutation rate baked into Influenza’s reproduction cycle is much more elaborate than coronaviruses, and this isn’t exactly a bad thing. When a human catches bird flu from a bird, the mortality rates are pretty burly as this version of the virus attaches to the α2:3 receptor. While this receptor is found throughout the avian digestive and respiratory track, it’s only found in the lower lungs of humans. A lower lung infection will always be gnarlier than an upper respiratory infection. Human influenza viruses have a preference for the α2:6 receptor, which is found throughout our airway. This is the primary adaptation which occurs when influenza mutates to infect humans. But a virus is a parasite, so in their ideal world, they wouldn’t kill their host. Viruses often do the most damage when adapting to or having recently adapted to a new host. Hopefully, the mutation rate of influenza will result in a shorter pandemic compared to COVID if it ends up taking place.